Alkynyl myristic acid is can be used to identify and characterize the post-translational myristylated proteins Alkynyl palmitic acid (15-hexadecynoic acid or Palmitic acid (15-yne)) is a modified palmitic acid with an ω-terminal alkyne. Alkynyl palmitic acid often used to identify and characterize the post-translational S-palmitoylation of proteins using the powerful click chemistry相互融合。
炔基肉豆蔻酸可用于鑒定和表征翻譯后肉豆蔻酸的炔基棕櫚酸(15-十六烷酸或棕櫚酸(15-炔))是一種具有ω末端炔烴的改性棕櫚酸。炔基棕櫚酸常用于使用強大的點擊化學來鑒定和表征蛋白質的翻譯后S-棕櫚踅Y構;焖僭鲩L。
Alkynyl Palmitic Acid (Alk-C16) 是一種 PROTAC linker,屬于 alkyl chain 類管理√嵘??捎糜诤铣?PROTAC 分子參與能力。Alkynyl Palmitic Acid 是一種點擊化學試劑自動化。它含有 Alkyne 基團提升,可以和含有 Azide 基團的分子發(fā)生銅催化的疊氮-炔環(huán)加成反應 (CuAAc)。
請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液不折不扣;一旦配成溶液支撐能力,請分裝保存,避免反復凍融造成的產(chǎn)品失效高效利用。
儲備液的保存方式和期限:-80°C, 6 months; -20°C, 1 month特征更加明顯。-80°C儲存時,請在6個月內使用講理論,-20°C儲存時的可能性,請在1個月內使用。
1. Gray, R. A. V., et al. (2021). Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry. JoVE Journal, 10 (3791), 62107.
2. Li, B., et al. (2020). TMEM132A, a Novel Wnt Signaling Pathway Regulator Through Wntless (WLS) Interaction. Front Cell Dev Biol., 8, 599890.
3. Lee, M.T., et al. (2020). Dietary sphinganine is selectively assimilated by members of themammaliangut microbiome. J Lipid Res .
4. White, F. K. H., et al. (2019). S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane. J Biol Chem., 294 (36), 13487-13501.
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