Alkynyl myristic acid is can be used to identify and characterize the post-translational myristylated proteins Alkynyl palmitic acid (15-hexadecynoic acid or Palmitic acid (15-yne)) is a modified palmitic acid with an ω-terminal alkyne. Alkynyl palmitic acid often used to identify and characterize the post-translational S-palmitoylation of proteins using the powerful click chemistry。

炔基肉豆蔻酸可用于鑒定和表征翻譯后肉豆蔻酸的炔基棕櫚酸（15-十六烷酸或棕櫚酸（15-炔））是一種具有ω末端炔烴的改性棕櫚酸與時俱進。炔基棕櫚酸常用于使用強(qiáng)大的點(diǎn)擊化學(xué)來(lái)鑒定和表征蛋白質(zhì)的翻譯后S-棕櫚醢l展契機；纶厔?。

Alkynyl Palmitic Acid (Alk-C16) 是一種 PROTAC linker示範推廣，屬于 alkyl chain 類(lèi)相對簡便”憷?？捎糜诤铣?PROTAC 分子自主研發。Alkynyl Palmitic Acid 是一種點(diǎn)擊化學(xué)試劑機製。它含有 Alkyne 基團(tuán)全過程，可以和含有 Azide 基團(tuán)的分子發(fā)生銅催化的疊氮-炔環(huán)加成反應(yīng) (CuAAc)。

請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液探討；一旦配成溶液不負眾望，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效調解製度。
儲(chǔ)備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month精準調控。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)月內(nèi)使用應用的因素之一，-20°C儲(chǔ)存時(shí)解決，請(qǐng)?jiān)?個(gè)月內(nèi)使用預期。

Selected References參考文獻(xiàn)

1. Gray, R. A. V., et al. (2021). Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry. JoVE Journal, 10 (3791), 62107.

2. Li, B., et al. (2020). TMEM132A, a Novel Wnt Signaling Pathway Regulator Through Wntless (WLS) Interaction. Front Cell Dev Biol., 8, 599890.

3. Lee, M.T., et al. (2020). Dietary sphinganine is selectively assimilated by members of themammaliangut microbiome. J Lipid Res .

4. White, F. K. H., et al. (2019). S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane. J Biol Chem., 294 (36), 13487-13501.