BTTAA 是最新一代的 CuAAC 水溶性加速配體顯著，與上一代配體（例如 THPTA 或 TBTA）相比充分發揮，它提供了更大的速率增強(qiáng)情況較常見。更重要的是數據顯示，它最大限度地減少了對(duì)所探測(cè)細(xì)胞或生物體生理狀態(tài)的擾動(dòng)作用，并通過進(jìn)一步降低催化劑配方中的銅負(fù)載量進行培訓，實(shí)現(xiàn)了有效的生物偶聯(lián)信息化，抑制了細(xì)胞毒性註入新的動力。

BTTAA is a newest generation, water-soluble accelerating ligand for CuAAC that provides much greater rate enhancement compared to previous generation ligands (e.g. THPTA or TBTA). More importantly, it minimizes perturbations to the physiological state of the cells or organisms probed and allows for effective bioconjugation with suppressed cell cytotoxicity by further lowering copper loading in the catalyst formulation.